EPD i. MassIVE i. MaxQB i. PaxDb, a database of protein abundance averages across all three domains of life More PaxDb i. PeptideAtlas More PeptideAtlas i. PRIDE i. ProteomicsDB: a multi-organism proteome resource More ProteomicsDB i.
GlyGen i. MetOSite database of methionine sulfoxide sites More MetOSite i. PhosphoSitePlus i. SwissPalm database of S-palmitoylation events More SwissPalm i. Bgee i. ExpressionAtlas i. Genevisible search portal to normalized and curated expression data from Genevestigator More Genevisible i. Human Protein Atlas More HPA i. BioGRID i. ComplexPortal: manually curated resource of macromolecular complexes More ComplexPortal i. CORUM i. Database of interacting proteins More DIP i. Protein interaction database and analysis system More IntAct i.
Molecular INTeraction database More MINT i. RNAct i. SMR i. Database of comparative protein structure models More ModBase i. PDBe-KB i. Ensembl GeneTree More GeneTree i. InParanoid i. OMA i. Database of Orthologous Groups More OrthoDB i. Database for complete collections of gene phylogenies More PhylomeDB i. TreeFam database of animal gene trees More TreeFam i. Gene3D i. Integrated resource of protein families, domains and functional sites More InterPro i.
Pfam protein domain database More Pfam i. Protein Motif fingerprint database; a protein domain database More SMART i. Superfamily database of structural and functional annotation More These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples.
Objective: SOX10 is a critical regulator in melanocytes and melanoma cells, but its specific role in their proliferation is far from clear. In this study we analyze the role of SOX10 in regulating mammalian melanocyte proliferation in a mouse model. Results: Reduction of Sox10 gene dose led to a reduction in the number of melanoblasts.
Knockdown of Sox10 in melanocytes led to inhibition of cell proliferation and a decrease in the expression of the minichromosome maintenance complex component 5 MCM5. You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser. The new UniProt website is here! Your basket is currently empty. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence s displayed.
Select a section on the left to see content. Search chemical reactions in Rhea for this molecule. See the description of this molecule in ChEBI. See the description of this reaction in Rhea. Show » « Hide. Alternative name s :. Nucleic Acids Res. SwissPalm i P ModBase i Search The information is filed in different subsections. Length: Mass Da : 82, It is useful for tracking sequence updates. The algorithm is described in the ISO standard.
The sequence BAA differs from that shown. Reason: Frameshift. Full view. These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary citable accession number'.
See complete history. Do not show this banner again. It always involves more than one amino acid and includes all residues involved in nucleotide-binding. ATP Sequence analysis. DNA-binding , Helicase , Hydrolase. Cell cycle , DNA replication. ATP-binding , Nucleotide-binding. Reactome - a knowledgebase of biological pathways and processes More Reactome i. Search reactions for this EC number in Rhea.
Mus musculus Mouse. This is known as the 'taxonomic identifier' or 'taxid'. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.
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